|Application ||WB, IHC-P, IF|
|Dilution||IHC-P (2.5 µg/ml), WB (0.5-2 µg/ml),|
|Other Names||ADP-ribosylation factor-like protein 6-interacting protein 1, ARL-6-interacting protein 1, Aip-1, ARL6IP1, ARL6IP, KIAA0069|
|Target/Specificity||peptide corresponding to 15 amino acids near the C-terminus of human ARMER|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||ARL6IP1 / ARMER Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.|
|Cellular Location||Endomembrane system; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Note=Predominantly localized to intracytoplasmic membranes|
|Tissue Location||Expressed in all hematopoietic cell lineages, but the highest level of expression is found in early myeloid progenitor cells. Expressed in brain, bone marrow, thymus and lung. Expressed at low level in liver, kidney and spleen. Not detected in heart.|
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Provided below are standard protocols that you may find useful for product applications.
May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.
Nomura N.,et al.DNA Res. 1:223-229(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Martin J.,et al.Nature 432:988-994(2004).
Pettersson M.,et al.Genomics 68:351-354(2000).
Kuroda M.,et al.FEBS Lett. 587:3656-3660(2013).
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