|Application ||WB, IHC-P, IF|
|Dilution||IHC-P (5 µg/ml), WB (0.5-1 µg/ml),|
|Other Names||Cadherin-13, Heart cadherin, H-cadherin, P105, Truncated cadherin, T-cad, T-cadherin, CDH13, CDHH|
|Target/Specificity||15 amino acid peptide from near the amino terminus of human T-cadherin|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||CDH13 / Cadherin 13 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor.|
|Tissue Location||Highly expressed in heart. In the CNS, expressed in cerebral cortex, medulla, hippocampus, amygdala, thalamus and substantia nigra. No expression detected in cerebellum or spinal cord.|
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Provided below are standard protocols that you may find useful for product applications.
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. May act as a negative regulator of neural cell growth.
Tanihara H.,et al.Cell Adhes. Commun. 2:15-26(1994).
Lee S.W.,et al.Nat. Med. 2:776-782(1996).
Sato M.,et al.Hum. Genet. 103:96-101(1998).
Liu Q.-R.,et al.Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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