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S1PR4 / SIP4 / EDG6 Antibody

Rabbit Polyclonal Antibody

     
  • IHC - S1PR4 / SIP4 / EDG6 Antibody ALS11418
    Anti-EDG6 antibody IHC of human tonsil.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession O95977
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 42kDa
Dilution ELISA (1:1000), IHC-P (10 µg/ml),
Additional Information
Gene ID 8698
Other Names Sphingosine 1-phosphate receptor 4, S1P receptor 4, S1P4, Endothelial differentiation G-protein coupled receptor 6, Sphingosine 1-phosphate receptor Edg-6, S1P receptor Edg-6, S1PR4, EDG6
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsS1PR4 / SIP4 / EDG6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name S1PR4
Synonyms EDG6
Function Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Specifically expressed in fetal and adult lymphoid and hematopoietic tissue as well as in lung. Considerable level of expression in adult and fetal spleen as well as adult peripheral leukocytes and lung. Lower expression in adult thymus, lymph node, bone marrow, and appendix as well as in fetal liver, thymus, and lung
Research Areas
Citations (0)

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Background

Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.

References

Graeler M.H.,et al.Genomics 53:164-169(1998).
Kopatz S.A.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Yamazaki Y.,et al.Biochem. Biophys. Res. Commun. 268:583-589(2000).
Van Brocklyn J.R.,et al.Blood 95:2624-2629(2000).

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$ 395.00
Cat# ALS11418
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