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NGFRAP1 / NADE / Bex Antibody

Rabbit Polyclonal Antibody

     
  • WB - NGFRAP1 / NADE / Bex Antibody ALS11423
    Western blot of NADE in Human brain cell lysates with NADE antibody at 1 ug/ml in the presence...
  • IHC - NGFRAP1 / NADE / Bex Antibody ALS11423
    Anti-NGFRAP1 / NADE antibody IHC of human brain, cortex.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q00994
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 13kDa
Dilution IHC-P (5 µg/ml), WB (0.5-2 µg/ml),
Additional Information
Gene ID 27018
Other Names Protein BEX3, Brain-expressed X-linked protein 3, Nerve growth factor receptor-associated protein 1, Ovarian granulosa cell 13.0 kDa protein HGR74, p75NTR-associated cell death executor, NGFRAP1, BEX3, DXS6984E, NADE
Target/Specificity peptide corresponding to 14 amino acids near the middle of human NADE
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsNGFRAP1 / NADE / Bex Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BEX3 (HGNC:13388)
Function May be a signaling adapter molecule involved in p75NTR- mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.
Cellular Location Nucleus. Cytoplasm. Note=Shuttles between the cytoplasm and the nucleus. Associates with replicating mitochondria (By similarity).
Tissue Location Found in ovarian granulosa cells, testis, prostate and seminal vesicle tissue. High levels also detected in liver.
Research Areas
Citations (0)

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Background

May be a signaling adapter molecule involved in p75NTR- mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death (By similarity). May play an important role in the pathogenesis of neurogenetic diseases.

References

Rapp G.,et al.DNA Cell Biol. 9:479-485(1990).
Mukai J.,et al.J. Biol. Chem. 275:17566-17570(2000).
Alvarez E.,et al.Gene 357:18-28(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zhou X.,et al.Mol. Vis. 13:2214-2221(2007).

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$ 395.00
Cat# ALS11423
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