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PDCD1 / CD279 / PD-1 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - PDCD1 / CD279 / PD-1 Antibody (C-Terminus) ALS11431
    Immunofluorescence of PD-1 in Human Brain cells with PD-1 antibody at 20 ug/ml.
  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q15116
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 32kDa
Dilution IHC-P (2.5 µg/ml)
Additional Information
Gene ID 5133
Other Names Programmed cell death protein 1, Protein PD-1, hPD-1, CD279, PDCD1, PD1
Target/Specificity 16 amino acid peptide from near the carboxy terminus of human PDCD1.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsPDCD1 / CD279 / PD-1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PDCD1
Synonyms PD1
Function Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors.

References

Shinohara T.,et al.Genomics 23:704-706(1994).
Finger L.R.,et al.Gene 197:177-187(1997).
Finger L.R.,et al.Gene 203:253-253(1997).
Prokunina L.,et al.Nat. Genet. 32:666-669(2002).
He X.,et al.Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS11431
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