|Application ||WB, IHC-P, IF|
|Dilution||IHC-P (2.5 µg/ml)|
|Other Names||Protein SCO2 homolog, mitochondrial, SCO2|
|Target/Specificity||19 amino acid peptide from near the carboxy terminus of human SCO2.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||SCO2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2 (PubMed:15229189, PubMed:17189203). Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2 (PubMed:19336478).|
|Cellular Location||Mitochondrion inner membrane; Single-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Acts as a copper chaperone, transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2).
Papadopoulou L.C.,et al.Nat. Genet. 23:333-337(1999).
Collins J.E.,et al.Genome Res. 13:27-36(2003).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Banci L.,et al.Structure 15:1132-1140(2007).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.