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SCO2 Antibody (C-Terminus)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF |
|---|---|
| Primary Accession | O43819 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 30kDa |
| Dilution | IHC-P (2.5 µg/ml) |
| Gene ID | 9997 |
|---|---|
| Other Names | Protein SCO2 homolog, mitochondrial, SCO2 |
| Target/Specificity | 19 amino acid peptide from near the carboxy terminus of human SCO2. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted. |
| Precautions | SCO2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SCO2 |
|---|---|
| Function | Copper metallochaperone essential for the synthesis and maturation of cytochrome c oxidase subunit II (MT-CO2/COX2). Involved in transporting copper to the Cu(A) site on MT-CO2/COX2 (PubMed:15229189, PubMed:17189203). Also acts as a thiol-disulfide oxidoreductase to regulate the redox state of the cysteines in SCO1 during maturation of MT-CO2/COX2 (PubMed:19336478). |
| Cellular Location | Mitochondrion inner membrane; Single-pass membrane protein |
| Tissue Location | Ubiquitous. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Acts as a copper chaperone, transporting copper to the Cu(A) site on the cytochrome c oxidase subunit II (COX2).
References
Papadopoulou L.C.,et al.Nat. Genet. 23:333-337(1999).
Collins J.E.,et al.Genome Res. 13:27-36(2003).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
Banci L.,et al.Structure 15:1132-1140(2007).
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