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IL31 Antibody (Internal)

Rabbit Polyclonal Antibody

     
  • IF - IL31 Antibody (Internal) ALS11465
    Immunofluorescence of IL-31 in Human Skeletal Muscle cells with IL-31 antibody at 20 ug/ml.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q6EBC2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 18kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 386653
Other Names Interleukin-31, IL-31, IL31
Target/Specificity 18 amino acid peptide from near the center of human IL-31
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsIL31 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL31
Function Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR (PubMed:15184896). May function in skin immunity (PubMed:15184896). Enhances myeloid progenitor cell survival in vitro (By similarity). Induces RETNLA and serum amyloid A protein expression in macrophages (By similarity).
Cellular Location Secreted.
Tissue Location Detected at low levels in testis, bone marrow, skeletal muscle, kidney, colon, thymus, small intestine and trachea.
Research Areas
Citations (0)

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Background

Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. IL31 may function in skin immunity.

References

Dillon S.R.,et al.Nat. Immunol. 5:752-760(2004).
Bilsborough J.,et al.J. Allergy Clin. Immunol. 117:418-425(2006).
Neis M.M.,et al.J. Allergy Clin. Immunol. 118:930-937(2006).

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$ 395.00
Cat# ALS11465
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