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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TNFRSF12A / FN14 Antibody   

TNFRSF12A / FN14 Antibody

Rabbit Polyclonal Antibody

     
  • IF - TNFRSF12A / FN14 Antibody ALS11495
    Immunofluorescence of Fn14 in Human Liver cells with Fn14 antibody at 20 ug/ml.
  • IHC - TNFRSF12A / FN14 Antibody ALS11495
    Anti-TWEAKR antibody IHC of human kidney.
  • IHC - TNFRSF12A / FN14 Antibody ALS11495
    Anti-TWEAKR antibody IHC of human placenta.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q9NP84
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 14kDa
Dilution IHC-P (2, 2.5 µg/ml), WB (1 µg/ml),
Additional Information
Gene ID 51330
Other Names Tumor necrosis factor receptor superfamily member 12A, Fibroblast growth factor-inducible immediate-early response protein 14, FGF-inducible 14, Tweak-receptor, TweakR, CD266, TNFRSF12A, FN14
Target/Specificity human IgG1 Fc-tagged Fn14 protein
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsTNFRSF12A / FN14 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFRSF12A
Synonyms FN14
Function Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas
Research Areas
Citations (0)

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Background

Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.

References

Feng S.-L.Y.,et al.Am. J. Pathol. 156:1253-1261(2000).
Tanaka S.,et al.Submitted (DEC-1999) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Wiley S.R.,et al.Immunity 15:837-846(2001).
He F.,et al.Protein Sci. 18:650-656(2009).

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$ 395.00
Cat# ALS11495
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