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>   home   >   Products   >   Primary Antibodies   >   UNG / Uracil DNA Glycosylase Antibody (C-Terminus)   

UNG / Uracil DNA Glycosylase Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IF - UNG / Uracil DNA Glycosylase Antibody (C-Terminus) ALS11504
    Immunofluorescence of UNG1 in Human Heart cells with UNG1 antibody at 20 ug/ml.
    detail
  • IHC - UNG / Uracil DNA Glycosylase Antibody (C-Terminus) ALS11504
    Anti-UNG antibody IHC of human heart.
    detail
  • IHC - UNG / Uracil DNA Glycosylase Antibody (C-Terminus) ALS11504
    Anti-UNG antibody IHC of human testis.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession P13051
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 35kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 7374
Other Names Uracil-DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_03166}, UDG {ECO:0000255|HAMAP-Rule:MF_03166}, 3.2.2.27 {ECO:0000255|HAMAP-Rule:MF_03166}, UNG {ECO:0000255|HAMAP-Rule:MF_03166}
Target/Specificity 14 amino acid peptide from near the carboxy terminus of human UNG1
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsUNG / Uracil DNA Glycosylase Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UNG {ECO:0000255|HAMAP-Rule:MF_03166}
Function Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
Cellular Location [Isoform 1]: Mitochondrion.
Tissue Location Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest expression levels in tissues containing proliferating cells
Citations (0)
citation

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Background

Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.

References

Olsen L.C.,et al.EMBO J. 8:3121-3125(1989).
Haug T.,et al.FEBS Lett. 353:180-184(1994).
Nilsen H.,et al.Nucleic Acids Res. 25:750-755(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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Discontinued
Cat# ALS11504
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