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>   home   >   Products   >   Primary Antibodies   >   DUT / DUTPase Antibody (aa1-52)   

DUT / DUTPase Antibody (aa1-52)

Chicken Polyclonal Antibody

     
  • IHC - DUT / DUTPase Antibody (aa1-52) ALS11544
    Anti-DUT antibody IHC of human kidney.
  • IHC - DUT / DUTPase Antibody (aa1-52) ALS11544
    Anti-DUT antibody IHC of human pancreas.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P33316
Reactivity Human
Host Chicken
Clonality Polyclonal
Calculated MW 27kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 1854
Other Names Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial, dUTPase, 3.6.1.23, dUTP pyrophosphatase, DUT
Target/Specificity Amino acids 1-52 of human DUT
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsDUT / DUTPase Antibody (aa1-52) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUT
Function This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
Cellular Location Isoform 2: Nucleus
Tissue Location Found in a variety of tissues. Isoform 3 expression is constitutive, while isoform 2 expression correlates with the onset of DNA replication (at protein level). Isoform 2 degradation coincides with the cessation of nuclear DNA replication (at protein level).
Citations (0)

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Background

This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

References

Ladner R.D.,et al.J. Biol. Chem. 271:7745-7751(1996).
Cohen D.,et al.Genomics 40:213-215(1997).
Pearlman R.E.,et al.Submitted (OCT-1997) to the EMBL/GenBank/DDBJ databases.
Ladner R.D.,et al.J. Biol. Chem. 272:19072-19080(1997).
Chano T.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS11544
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