|Application ||IHC-P, E|
|Dilution||ELISA (1:1000), IHC-P (10 µg/ml),|
|Other Names||Growth/differentiation factor 3, GDF-3, GDF3|
|Target/Specificity||Amino acids 35 to 53 of human GDF3|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||GDF3 Antibody (aa35-53) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Growth factor involved in early embryonic development and adipose-tissue homeostasis. During embryogenesis controls formation of anterior visceral endoderm and mesoderm and the establishment of anterior-posterior identity through a receptor complex comprising the receptor ACVR1B and the coreceptor TDGF1/Cripto (By similarity). Regulates adipose-tissue homeostasis and energy balance under nutrient overload in part by signaling through the receptor complex based on ACVR1C and TDGF1/Cripto (PubMed:21805089).|
|Cellular Location||Secreted. Cytoplasm Note=Mainly accumulated in the cytoplasm|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Lorenz B.,et al.Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ye M.,et al.Hum. Mol. Genet. 19:287-298(2010).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.