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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MMP17 Antibody (aa409-423)   

MMP17 Antibody (aa409-423)

Rabbit Polyclonal Antibody

     
  • IHC - MMP17 Antibody (aa409-423) ALS11592
    Anti-MMP17 antibody IHC of human small intestine.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession Q9ULZ9
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 67kDa
Dilution ELISA (1:1000), IHC-P (3-5 µg/ml),
Additional Information
Gene ID 4326
Other Names Matrix metalloproteinase-17, MMP-17, 3.4.24.-, Membrane-type matrix metalloproteinase 4, MT-MMP 4, MTMMP4, Membrane-type-4 matrix metalloproteinase, MT4-MMP, MT4MMP, MMP17, MT4MMP
Target/Specificity Amino acids 409 to 423 of human MMP17
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsMMP17 Antibody (aa409-423) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMP17
Synonyms MT4MMP
Function Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.
Cellular Location Isoform Long: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side. Secreted, extracellular space, extracellular matrix
Tissue Location Expressed in brain, leukocytes, colon, ovary testis and breast cancer. Expressed also in many transformed and non-transformed cell types
Research Areas
Citations (0)

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Background

Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.

References

Kajita M.,et al.FEBS Lett. 457:353-356(1999).
Seiki M.,et al.Submitted (JAN-2002) to the EMBL/GenBank/DDBJ databases.
Puente X.S.,et al.Cancer Res. 56:944-949(1996).
Scherer S.E.,et al.Nature 440:346-351(2006).
Wang Y.,et al.J. Biol. Chem. 274:33043-33049(1999).

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$ 395.00
Cat# ALS11592
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