|Dilution||IHC-P (5 µg/ml)|
|Other Names||T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2, CD8a, CD8A, MAL|
|Target/Specificity||Peptide corresponding to the C-terminal amino acids of the cytoplasmic domain of human CD8 alpha chain|
|Reconstitution & Storage||+4°C, avoid freezing|
|Precautions||CD8A / CD8 Alpha Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.|
|Cellular Location||Isoform 1: Cell membrane; Single-pass type I membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains.
Littman D.R.,et al.Cell 40:237-246(1985).
Parnes J.R.,et al.Behring Inst. Mitt. 77:48-55(1985).
Sukhatme V.P.,et al.Cell 40:591-597(1985).
Nakayama K.,et al.Immunogenetics 30:393-397(1989).
Norment A.M.,et al.J. Immunol. 142:3312-3319(1989).
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