|Application ||WB, IHC-P, IF|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Protein Niban, Cell growth-inhibiting gene 39 protein, Protein FAM129A, FAM129A, C1orf24, NIBAN|
|Target/Specificity||Peptide corresponding to amino acids 908 to 920 of human FAM129A|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||FAM129A / NIBAN Antibody (aa908-920) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response (By similarity).|
|Cellular Location||Cytoplasm. Membrane; Lipid-anchor|
|Tissue Location||Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with moderate expression in colon and spleen Expressed in renal carcinoma cells but not in normal kidney|
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Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response (By similarity).
Majima S.,et al.Jpn. J. Cancer Res. 91:869-874(2000).
Sood R.,et al.Genomics 73:211-222(2001).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kim J.W.,et al.Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
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