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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CAMK2A / CaMKII Alpha Antibody (Thr286)   

CAMK2A / CaMKII Alpha Antibody (Thr286)

Rabbit Polyclonal Antibody

     
  • IHC - CAMK2A / CaMKII Alpha Antibody (Thr286) ALS11625
    Anti-CAMK2A antibody IHC of human brain, cerebellum.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession Q9UQM7
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 54kDa
Dilution IHC-P (20 µg/ml)
Additional Information
Gene ID 815
Other Names Calcium/calmodulin-dependent protein kinase type II subunit alpha, CaM kinase II subunit alpha, CaMK-II subunit alpha, 2.7.11.17, CAMK2A, CAMKA, KIAA0968
Target/Specificity Amino acids surrounding Serine 286 of human CAMK2A
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsCAMK2A / CaMKII Alpha Antibody (Thr286) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CAMK2A
Synonyms CAMKA, KIAA0968
Function CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).
Cellular Location Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse Note=Postsynaptic lipid rafts.
Research Areas
Citations (0)

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Background

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).

References

Li G.Y.,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 6:63-70(1999).
Schmutz J.,et al.Nature 431:268-274(2004).
Krapivinsky G.,et al.Neuron 43:563-574(2004).

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$ 395.00
Cat# ALS11625
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