|Application ||WB, IHC-P|
|Reactivity||Human, Monkey, Bovine|
|Dilution||IHC-P (10 µg/ml), WB (0.5-2 µg/ml),|
|Other Names||Metalloreductase STEAP1, 1.16.1.-, Six-transmembrane epithelial antigen of prostate 1, STEAP1, PRSS24, STEAP|
|Target/Specificity||Peptide at the N-terminus of human STEAP1, located between amino acids 1 and 31.|
|Reconstitution & Storage||Store at 2-8°C for up to 1 year. Avoid repeated freeze-thaw cycles.|
|Precautions||STEAP1 / STEAP Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).|
|Cellular Location||Endosome membrane; Multi-pass membrane protein|
|Tissue Location||Ubiquitously expressed. Highly expressed in prostate tumors.|
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Provided below are standard protocols that you may find useful for product applications.
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).
Hubert R.S.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:14523-14528(1999).
Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).
Ohgami R.S.,et al.Blood 108:1388-1394(2006).
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