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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   RPAIN Antibody (C-Terminus)   

RPAIN Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - RPAIN Antibody (C-Terminus) ALS11712
    Anti-RPAIN antibody IHC of human adrenal.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q86UA6
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 25kDa
Dilution IHC-P (5 µg/ml), WB (0.5-1 µg/ml),
Additional Information
Gene ID 84268
Other Names RPA-interacting protein, hRIP, RPAIN, RIP
Target/Specificity 17 amino acid peptide from near the carboxy terminus of human RPA IP.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsRPAIN Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPAIN
Synonyms RIP
Function Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism.
Cellular Location Isoform 1: Cytoplasm. Nucleus.
Tissue Location Widely expressed. Expressed in pancreas, kidney, muscle, liver, lung, placenta, brain, heart, leukocytes, colon, intestine, ovary, testis, prostate, thymus and spleen
Research Areas
Citations (0)

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Background

Mediates the import of RPA complex into the nucleus, possibly via some interaction with importin beta. Isoform 2 is sumoylated and mediates the localization of RPA complex into the PML body of the nucleus, thereby participating in RPA function in DNA metabolism.

References

Chen J.-Z.,et al.DNA Cell Biol. 24:464-469(2005).
Park J.,et al.Mol. Cell. Biol. 25:8202-8214(2005).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Zody M.C.,et al.Nature 440:1045-1049(2006).
Gauci S.,et al.Anal. Chem. 81:4493-4501(2009).

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$ 395.00
Cat# ALS11712
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