|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1 µg/ml),|
|Other Names||Metalloreductase STEAP2, 1.16.1.-, Prostate cancer-associated protein 1, Protein up-regulated in metastatic prostate cancer, PUMPCn, Six-transmembrane epithelial antigen of prostate 2, SixTransMembrane protein of prostate 1, STEAP2, PCANAP1, STAMP1|
|Target/Specificity||a 16 amino acid peptide from near the carboxy terminus of human STEAP2|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||STEAP2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).|
|Cellular Location||Endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary.|
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Provided below are standard protocols that you may find useful for product applications.
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).
Korkmaz K.S.,et al.J. Biol. Chem. 277:36689-36696(2002).
Porkka K.P.,et al.Lab. Invest. 82:1573-1582(2002).
Zhang Z.,et al.Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Hillier L.W.,et al.Nature 424:157-164(2003).
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