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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   TLR5 Antibody (C-Terminus)   

TLR5 Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - TLR5 Antibody (C-Terminus) ALS11726
    Anti-TLR5 antibody IHC of human lung.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession O60602
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Calculated MW 98kDa
Dilution IHC-P (5 µg/ml), WB (1-2 µg/ml),
Additional Information
Gene ID 7100
Other Names Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3, TLR5, TIL3
Target/Specificity peptide corresponding to 15 amino acids near the carboxy terminus of human TLR5
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsTLR5 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TLR5
Synonyms TIL3
Function Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis
Research Areas
Citations (0)

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Background

Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

References

Chaudhary P.M.,et al.Blood 91:4020-4027(1998).
Seya T.,et al.Submitted (APR-2001) to the EMBL/GenBank/DDBJ databases.
Nakajima T.,et al.Immunogenetics 60:727-735(2008).
Wlasiuk G.,et al.Mol. Biol. Evol. 26:937-949(2009).
Georgel P.,et al.PLoS ONE 4:E7803-E7803(2009).

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$ 395.00
Cat# ALS11726
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