|Application ||WB, IHC-P|
|Dilution||IHC-P (5 µg/ml), WB (2 µg/ml),|
|Other Names||Protein orai-2, CAP-binding protein complex-interacting protein 2, Transmembrane protein 142B, ORAI2, C7orf19, CBCIP2, TMEM142B|
|Target/Specificity||an 15 amino acid peptide from near the carboxy terminus of human ORAI2|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||ORAI2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C7orf19, CBCIP2, TMEM142B|
|Function||Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1.|
|Cellular Location||Membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Ca(2+) release-activated Ca(2+)-like (CRAC-like) channel subunit which mediates Ca(2+) influx and increase in Ca(2+)- selective current by synergy with the Ca(2+) sensor, STIM1.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Wan D.,et al.Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Mercer J.C.,et al.J. Biol. Chem. 281:24979-24990(2006).
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