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TNFRSF14 / CD270 / HVEM Antibody (C-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - TNFRSF14 / CD270 / HVEM Antibody (C-Terminus) ALS11731
    Anti-TNFRSF14 / CD270 antibody IHC of human brain, cortex.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, ICC
Primary Accession Q92956
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 30kDa
Dilution IHC-P (5 µg/ml), WB (2 µg/ml),
Additional Information
Gene ID 8764
Other Names Tumor necrosis factor receptor superfamily member 14, Herpes virus entry mediator A, Herpesvirus entry mediator A, HveA, Tumor necrosis factor receptor-like 2, TR2, CD270, TNFRSF14, HVEA, HVEM
Target/Specificity 16 amino acid peptide from near the carboxy terminus of human TNFRSF14
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
PrecautionsTNFRSF14 / CD270 / HVEM Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TNFRSF14
Synonyms HVEA, HVEM
Function Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Widely expressed, with the highest expression in lung, spleen and thymus
Research Areas
Citations (0)

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Background

Receptor for BTLA. Receptor for TNFSF14/LIGHT and homotrimeric TNFSF1/lymphotoxin-alpha. Involved in lymphocyte activation. Plays an important role in HSV pathogenesis because it enhanced the entry of several wild-type HSV strains of both serotypes into CHO cells, and mediated HSV entry into activated human T-cells.

References

Montgomery R.I.,et al.Cell 87:427-436(1996).
Kwon B.S.,et al.J. Biol. Chem. 272:14272-14276(1997).
Zhang W.,et al.Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
Struyf F.,et al.J. Infect. Dis. 185:36-44(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS11731
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