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TS / Thymidylate Synthase Antibody

Sheep Polyclonal Antibody

     
  • WB - TS / Thymidylate Synthase Antibody ALS11757
    Anti-Thymidylate Synthase Antibody - Western Blot.
    detail
  • IHC - TS / Thymidylate Synthase Antibody ALS11757
    Anti-TYMS antibody IHC of human thymus.
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF, E, IP
Primary Accession P04818
Reactivity Human
Host Sheep
Clonality Polyclonal
Calculated MW 36kDa
Dilution IHC-P (5 µg/ml)
Additional Information
Gene ID 7298
Other Names Thymidylate synthase, TS, TSase, 2.1.1.45, TYMS, TS
Target/Specificity Recombinant human Thymidylate Synthase (36 kD) produced in E. coli.
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsTS / Thymidylate Synthase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TYMS (HGNC:12441)
Synonyms TS
Function Catalyzes the reductive methylation of 2'-deoxyuridine 5'- monophosphate (dUMP) to thymidine 5'-monophosphate (dTMP), using the cosubstrate, 5,10- methylenetetrahydrofolate (CH2H4folate) as a 1- carbon donor and reductant and contributes to the de novo mitochondrial thymidylate biosynthesis pathway.
Cellular Location Nucleus. Cytoplasm. Mitochondrion. Mitochondrion matrix. Mitochondrion inner membrane
Research Areas
Citations (0)
citation

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Background

Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.

References

Takeishi K.,et al.Nucleic Acids Res. 13:2035-2043(1985).
Kaneda S.,et al.J. Biol. Chem. 265:20277-20284(1990).
Hisatomi H.,et al.Cancer Lett. 193:127-131(2003).
Shichijo S.,et al.Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.
Nusbaum C.,et al.Nature 437:551-555(2005).

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$ 467.50
Cat# ALS11757
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