|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||M-phase inducer phosphatase 1, 188.8.131.52, Dual specificity phosphatase Cdc25A, CDC25A|
|Target/Specificity||Amino acids surrounding Ser 75 of human CDC25A|
|Reconstitution & Storage||Long term: -20°C; Short term: -20°C|
|Precautions||CDC25A Antibody (Ser75) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.|
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Provided below are standard protocols that you may find useful for product applications.
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.
Galaktionov K.I.,et al.Cell 67:1181-1194(1991).
Varmeh-Ziaie S.,et al.Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Wegener S.,et al.Eur. J. Cell Biol. 79:810-815(2000).
Falck J.,et al.Nature 410:842-847(2001).
Donzelli M.,et al.EMBO J. 21:4875-4884(2002).
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