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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KRT8 / CK8 / Cytokeratin 8 Antibody (Ser73)   

KRT8 / CK8 / Cytokeratin 8 Antibody (Ser73)

Rabbit Polyclonal Antibody

     
  • WB - KRT8 / CK8 / Cytokeratin 8 Antibody (Ser73) ALS11772
    Western blot of extracts from HUVEC and 293 cells using Keratin 8(Ab-74) antibody.
  • IF - KRT8 / CK8 / Cytokeratin 8 Antibody (Ser73) ALS11772
    Immunofluorescence staining of methanol-fixed HeLa cells using Keratin 8(Ab-74) antibody.
  • IHC - KRT8 / CK8 / Cytokeratin 8 Antibody (Ser73) ALS11772
    Anti-KRT8 / Cytokeratin 8 antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession P05787
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 54kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 3856
Other Names Keratin, type II cytoskeletal 8, Cytokeratin-8, CK-8, Keratin-8, K8, Type-II keratin Kb8, KRT8, CYK8
Target/Specificity Amino acids surrounding Ser 73 of human KRT8
Reconstitution & Storage Long term: -70°C; Short term: -20°C
PrecautionsKRT8 / CK8 / Cytokeratin 8 Antibody (Ser73) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT8
Synonyms CYK8
Function Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
Cellular Location Cytoplasm. Nucleus, nucleoplasm Nucleus matrix
Tissue Location Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
Research Areas
Citations (0)

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Background

Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

References

Krauss S.,et al.Gene 86:241-249(1990).
Yamamoto R.,et al.Mol. Endocrinol. 4:370-374(1990).
Waseem A.,et al.New Biol. 2:464-478(1990).
Ku N.-O.,et al.J. Biol. Chem. 272:7556-7564(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).

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$ 395.00
Cat# ALS11772
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