|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||14-3-3 protein zeta/delta, Protein kinase C inhibitor protein 1, KCIP-1, YWHAZ|
|Target/Specificity||Amino acids surrounding Ser 58 of human YWHAZ|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||YWHAZ / 14-3-3 Zeta Antibody (Ser58) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.|
|Cellular Location||Cytoplasm. Melanosome. Note=Located to stage I to stage IV melanosomes|
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Provided below are standard protocols that you may find useful for product applications.
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner.
Zupan L.A.,et al.J. Biol. Chem. 267:8707-8710(1992).
Seluja G.A.,et al.Biochim. Biophys. Acta 1395:281-287(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
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