|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Pig, Sheep|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Medium-chain specific acyl-CoA dehydrogenase, mitochondrial, MCAD, 188.8.131.52, ACADM|
|Target/Specificity||Human recombinant MCAD1|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||MCAD / ACADM Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acyl-CoA dehydrogenase specific for acyl chain lengths of 4 to 16 that catalyzes the initial step of fatty acid beta- oxidation. Utilizes the electron transfer flavoprotein (ETF) as an electron acceptor to transfer electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).|
|Cellular Location||Mitochondrion matrix.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This enzyme is specific for acyl chain lengths of 4 to 16.
Kelly D.P.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:4068-4072(1987).
Zhang Z.F.,et al.Biochemistry 31:81-89(1992).
Sun F.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
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