|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat, Hamster, Monkey, Pig, Horse, Bovine, Dog|
|Dilution||IHC-P (20 µg/ml)|
|Other Names||Prostacyclin synthase, 22.214.171.124, Prostaglandin I2 synthase, PTGIS, CYP8, CYP8A1|
|Target/Specificity||Murine prostaglandin I synthase (PGIS) amino acids 475-490 conjugated to KLH (PEFDLSRYGFGLMQPE)|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PGIS / PTGIS Antibody (aa475-490) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein|
|Tissue Location||Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).
Miyata A.,et al.Biochem. Biophys. Res. Commun. 200:1728-1734(1994).
Chevalier D.,et al.Hum. Genet. 108:148-155(2001).
Deloukas P.,et al.Nature 414:865-871(2001).
Chiang C.W.,et al.J. Mol. Biol. 364:266-274(2006).
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