|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat, Hamster, Monkey, Pig, Horse, Bovine, Dog|
|Dilution||IHC-P (20 µg/ml)|
|Other Names||Prostacyclin synthase, 188.8.131.52, Prostaglandin I2 synthase, PTGIS, CYP8, CYP8A1|
|Target/Specificity||Murine prostaglandin I synthase (PGIS) amino acids 475-490 conjugated to KLH (PEFDLSRYGFGLMQPE)|
|Reconstitution & Storage||Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.|
|Precautions||PGIS / PTGIS Antibody (aa475-490) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein|
|Tissue Location||Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).
Miyata A.,et al.Biochem. Biophys. Res. Commun. 200:1728-1734(1994).
Chevalier D.,et al.Hum. Genet. 108:148-155(2001).
Deloukas P.,et al.Nature 414:865-871(2001).
Chiang C.W.,et al.J. Mol. Biol. 364:266-274(2006).
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