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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PGIS / PTGIS Antibody (aa475-490)   

PGIS / PTGIS Antibody (aa475-490)

Rabbit Polyclonal Antibody

     
  • IHC - PGIS / PTGIS Antibody (aa475-490) ALS11793
    Anti-PTGIS antibody IHC of human heart.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q16647
Reactivity Human, Mouse, Rat, Hamster, Monkey, Pig, Horse, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 57kDa
Dilution IHC-P (20 µg/ml)
Additional Information
Gene ID 5740
Other Names Prostacyclin synthase, 5.3.99.4, Prostaglandin I2 synthase, PTGIS, CYP8, CYP8A1
Target/Specificity Murine prostaglandin I synthase (PGIS) amino acids 475-490 conjugated to KLH (PEFDLSRYGFGLMQPE)
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsPGIS / PTGIS Antibody (aa475-490) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTGIS
Synonyms CYP8, CYP8A1
Function Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).
Cellular Location Endoplasmic reticulum membrane; Single-pass membrane protein
Tissue Location Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate
Research Areas
Citations (0)

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Background

Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2).

References

Miyata A.,et al.Biochem. Biophys. Res. Commun. 200:1728-1734(1994).
Chevalier D.,et al.Hum. Genet. 108:148-155(2001).
Deloukas P.,et al.Nature 414:865-871(2001).
Chiang C.W.,et al.J. Mol. Biol. 364:266-274(2006).

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Discontinued
Cat# ALS11793
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