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PLA2G5 Antibody (clone MCL-3G1)

Mouse Monoclonal Antibody

     
  • IHC - PLA2G5 Antibody (clone MCL-3G1) ALS11810
    Anti-PLA2G5 antibody IHC of human heart.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IP
Primary Accession P39877
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names MCL-3G1
Calculated MW 16kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 5322
Other Names Calcium-dependent phospholipase A2, 3.1.1.4, Group V phospholipase A2, PLA2-10, Phosphatidylcholine 2-acylhydrolase 5, PLA2G5
Target/Specificity Purified recombinant human sPLA2 (type V)
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsPLA2G5 Antibody (clone MCL-3G1) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PLA2G5
Function PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L-alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L- alpha-1-palmitoyl-2-arachidonyl phosphatidylethanolamine, or L- alpha-1-stearoyl-2-arachidonyl phosphatidylinositol. May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle.
Cellular Location Secreted.
Tissue Location Heart, placenta and less abundantly, in lung. Detected in the outer and inner plexiform layers of the retina (at protein level).
Volume 1 ea
Research Areas
Citations (0)

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Background

PA2 catalyzes the calcium-dependent hydrolysis of the 2- acyl groups in 3-sn-phosphoglycerides. This isozyme hydrolyzes more efficiently L-alpha-1-palmitoyl-2-oleoyl phosphatidylcholine than L-alpha-1-palmitoyl-2-arachidonyl phosphatidylcholine, L- alpha-1-palmitoyl-2-arachidonyl phosphatidylethanolamine, or L- alpha-1-stearoyl-2-arachidonyl phosphatidylinositol. May be involved in the production of lung surfactant, the remodeling or regulation of cardiac muscle.

References

Chen J.,et al.J. Biol. Chem. 269:2365-2368(1994).
Gregory S.G.,et al.Nature 441:315-321(2006).
Sergouniotis P.I.,et al.Am. J. Hum. Genet. 89:782-791(2011).

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$ 395.00
Cat# ALS11810
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