|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Glutathione peroxidase 7, GPx-7, GSHPx-7, 22.214.171.124, CL683, GPX7, GPX6|
|Reconstitution & Storage||Long term: -70°C; Short term: -70°C|
|Precautions||GPX7 Antibody (clone 2704) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.|
|Tissue Location||Expressed in esophageal epithelial cells; expression is up-regulated after exposure to acidic bile acids|
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It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks.
Gu S.,et al.Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Gregory S.G.,et al.Nature 441:315-321(2006).
Barrow I.K.-P.,et al.Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
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