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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MAP2K2 / MKK2 / MEK2 Antibody (phospho-Thr394)   

MAP2K2 / MKK2 / MEK2 Antibody (phospho-Thr394)

Rabbit Polyclonal Antibody

     
  • IF - MAP2K2 / MKK2 / MEK2 Antibody (phospho-Thr394) ALS11883
    Immunofluorescence staining of methanol-fixed HeLa cells using MEK-2(Phospho-Thr394) antibody.
  • IHC - MAP2K2 / MKK2 / MEK2 Antibody (phospho-Thr394) ALS11883
    Anti-MAP2K2 / MEK2 antibody IHC of human skin.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, IF
Primary Accession P36507
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 44kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 5605
Other Names Dual specificity mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK 2, 2.7.12.2, ERK activator kinase 2, MAPK/ERK kinase 2, MEK 2, MAP2K2, MEK2, MKK2, PRKMK2
Target/Specificity Phosphopetide derived from human MEK2 around the phosphorylation site of threonine 394 (P-G-TP-P-T)
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsMAP2K2 / MKK2 / MEK2 Antibody (phospho-Thr394) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAP2K2
Synonyms MEK2, MKK2, PRKMK2
Function Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).
Cellular Location Cytoplasm. Membrane; Peripheral membrane protein. Note=Membrane localization is probably regulated by its interaction with KSR1
Research Areas
Citations (0)

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Background

Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates the ERK1 and ERK2 MAP kinases (By similarity).

References

Zheng C.-F.,et al.J. Biol. Chem. 268:11435-11439(1993).
Bienvenut W.V.,et al.Submitted (DEC-2008) to UniProtKB.
Mittal R.,et al.Proc. Natl. Acad. Sci. U.S.A. 103:18574-18579(2006).
Duesbery N.S.,et al.Science 280:734-737(1998).
Vitale G.,et al.Biochem. J. 352:739-745(2000).

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$ 395.00
Cat# ALS11883
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