OLIG1 Antibody (C-Terminus)
Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, E |
---|---|
Primary Accession | Q8TAK6 |
Reactivity | Human, Monkey |
Host | Goat |
Clonality | Polyclonal |
Calculated MW | 28kDa |
Dilution | ELISA (1:8000), IHC-P (2.5 µg/ml), |
Gene ID | 116448 |
---|---|
Other Names | Oligodendrocyte transcription factor 1, Oligo1, Class B basic helix-loop-helix protein 6, bHLHb6, Class E basic helix-loop-helix protein 21, bHLHe21, OLIG1, BHLHB6, BHLHE21 |
Target/Specificity | Human OLIG1. |
Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
Precautions | OLIG1 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | OLIG1 |
---|---|
Synonyms | BHLHB6, BHLHE21 |
Function | Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity). |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00981}. |
Tissue Location | Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas is highly variable. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Promotes formation and maturation of oligodendrocytes, especially within the brain. Cooperates with OLIG2 to establish the pMN domain of the embryonic neural tube (By similarity).
References
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Hattori M.,et al.Nature 405:311-319(2000).
McLellan A.S.,et al.Mech. Dev. 119:S285-S291(2002).
Zhou Q.,et al.Neuron 25:331-343(2000).
Lu Q.R.,et al.Proc. Natl. Acad. Sci. U.S.A. 98:10851-10856(2001).
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