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5-Alpha Reductase / SRD5A1 Antibody (N-Terminus)

Goat Polyclonal Antibody

     
  • IHC - 5-Alpha Reductase / SRD5A1 Antibody (N-Terminus) ALS11902
    Anti-SRD5A1 antibody IHC of human liver.
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  • SPECIFICATION
  • CITATIONS
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  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, E
Primary Accession P18405
Reactivity Human
Host Goat
Clonality Polyclonal
Calculated MW 29kDa
Dilution ELISA (1:64000), IHC-P (2.5 µg/ml),
Additional Information
Gene ID 6715
Other Names 3-oxo-5-alpha-steroid 4-dehydrogenase 1, 1.3.1.22, SR type 1, Steroid 5-alpha-reductase 1, S5AR 1, SRD5A1
Target/Specificity Human SRD5A1.
Reconstitution & Storage Store at -20°C. Minimize freezing and thawing.
Precautions5-Alpha Reductase / SRD5A1 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SRD5A1 (HGNC:11284)
Function Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5-alpha-3- oxosteroids. It plays a central role in sexual differentiation and androgen physiology.
Cellular Location Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Liver and prostate (at a low level).
Volume 50 µl
Research Areas
Citations (0)
citation

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Background

Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology.

References

Andersson S.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:3640-3644(1990).
Jenkins E.P.,et al.Genomics 11:1102-1112(1991).
Yu W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
Hu R.-M.,et al.Proc. Natl. Acad. Sci. U.S.A. 97:9543-9548(2000).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS11902
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