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C5AR2 / GPR77 / C5L2 Antibody (aa1-50)

Rabbit Polyclonal Antibody

     
  • WB - C5AR2 / GPR77 / C5L2 Antibody (aa1-50) ALS11912
    Western blot ofugPR77 in human testis?cell lysate in the 1) absence and 2) presence of...
  • IHC - C5AR2 / GPR77 / C5L2 Antibody (aa1-50) ALS11912
    Anti-C5L2 antibody IHC of human brain, cerebellum.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q9P296
Reactivity Human, Monkey, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 36kDa
Dilution IHC-P (10 µg/ml), WB (0.5-2 µg/ml),
Additional Information
Gene ID 27202
Other Names C5a anaphylatoxin chemotactic receptor 2, Complement component 5a receptor 2, G-protein coupled receptor 77, C5AR2, C5L2, GPR77
Target/Specificity A portion of amino acids 1-50 of human GPR77
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsC5AR2 / GPR77 / C5L2 Antibody (aa1-50) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name C5AR2
Synonyms C5L2, GPR77
Function Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways.
Cellular Location Cell membrane; Multi-pass membrane protein
Tissue Location Frontal cortex, hippocampus, hypothalamus, pons and liver.
Research Areas
Citations (0)

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Background

Receptor for the chemotactic and inflammatory C3a, C4a and C5a anaphylatoxin peptides and also for their dearginated forms ASP/C3adesArg, C4adesArg and C5adesArg respectively. Couples weakly to G(i)-mediated signaling pathways.

References

Ohno M.,et al.Mol. Immunol. 37:407-412(2000).
Lee D.K.,et al.Brain Res. Mol. Brain Res. 86:13-22(2001).
Kopatz S.A.,et al.Submitted (APR-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Grimwood J.,et al.Nature 428:529-535(2004).

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$ 395.00
Cat# ALS11912
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