|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Zebrafish, Monkey, Chicken, Bovine|
|Dilution||IHC-P (10 µg/ml), WB (1-3 µg/ml),|
|Other Names||Dual specificity protein phosphatase 16, 188.8.131.52, 184.108.40.206, Mitogen-activated protein kinase phosphatase 7, MAP kinase phosphatase 7, MKP-7, DUSP16, KIAA1700, MKP7|
|Target/Specificity||A portion of amino acids 600-650 of human DUSP16|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||DUSP16 / MKP7 Antibody (aa600-650) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.|
|Cellular Location||Cytoplasm. Nucleus. Cytoplasmic vesicle. Note=After dissociation upon AGTR stimulation, re-associates with ARRB2 on endocytic vesicles|
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Provided below are standard protocols that you may find useful for product applications.
Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2.
Masuda K.,et al.J. Biol. Chem. 276:39002-39011(2001).
Hoornaert I.,et al.Oncogene 22:7728-7736(2003).
Montpetit A.,et al.Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 7:347-355(2000).
Scherer S.E.,et al.Nature 440:346-351(2006).
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