|Application ||WB, IHC-P|
|Reactivity||Human, Mouse, Rat, Monkey, Chicken, Opossum, Horse, Xenopus, Bovine, Dog|
|Dilution||IHC-P (10 µg/ml), WB (0.5-2 µg/ml),|
|Other Names||Sorcin, 22 kDa protein, CP-22, CP22, V19, SRI|
|Target/Specificity||A portion of amino acids 50-100 of human Sorcin|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||SRI / Sorcin Antibody (aa50-100) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Calcium-binding protein that modulates excitation- contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.|
|Cellular Location||Cytoplasm. Sarcoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Note=Relocates to the sarcoplasmic reticulum membrane in response to elevated calcium levels|
|Tissue Location||Detected in cardiac myocytes.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Calcium-binding protein that modulates excitation- contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
Wang S.L.,et al.Biochim. Biophys. Acta 1260:285-293(1995).
Lee W.P.,et al.Arch. Biochem. Biophys. 325:217-226(1996).
Sugimoto Y.,et al.Submitted (MAR-1990) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Oh J.H.,et al.Mamm. Genome 16:942-954(2005).
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