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PPP1R1A / IPP1 Antibody (aa50-100)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | Q13522 |
| Reactivity | Human, Mouse, Rat, Monkey, Horse, Xenopus, Bovine, Dog |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 19kDa |
| Dilution | IHC-P (10 µg/ml), WB (0.5-2 µg/ml), |
| Gene ID | 5502 |
|---|---|
| Other Names | Protein phosphatase 1 regulatory subunit 1A, Protein phosphatase inhibitor 1, I-1, IPP-1, PPP1R1A, IPP1 |
| Target/Specificity | A portion of amino acids 50-100 of human IPP-1 |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | PPP1R1A / IPP1 Antibody (aa50-100) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PPP1R1A |
|---|---|
| Synonyms | IPP1 |
| Function | Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases. |
| Volume | 50 µl |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
References
Endo S.,et al.Biochemistry 35:5220-5228(1996).
Mishra S.,et al.Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Connor J.H.,et al.Mol. Cell. Biol. 21:6841-6850(2001).
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