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PPP1R1A / IPP1 Antibody (aa50-100)

Rabbit Polyclonal Antibody

     
  • WB - PPP1R1A / IPP1 Antibody (aa50-100) ALS11930
    Western blot of IPP-1 in human ovary lysate in the 1) absence and 2) presence of immunizing...
  • IHC - PPP1R1A / IPP1 Antibody (aa50-100) ALS11930
    Anti-PPP1R1A antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession Q13522
Reactivity Human, Mouse, Rat, Monkey, Horse, Xenopus, Bovine, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 19kDa
Dilution IHC-P (10 µg/ml), WB (0.5-2 µg/ml),
Additional Information
Gene ID 5502
Other Names Protein phosphatase 1 regulatory subunit 1A, Protein phosphatase inhibitor 1, I-1, IPP-1, PPP1R1A, IPP1
Target/Specificity A portion of amino acids 50-100 of human IPP-1
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsPPP1R1A / IPP1 Antibody (aa50-100) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPP1R1A
Synonyms IPP1
Function Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.
Volume 50 µl
Research Areas
Citations (0)

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Background

Inhibitor of protein-phosphatase 1. This protein may be important in hormonal control of glycogen metabolism. Hormones that elevate intracellular cAMP increase I-1 activity in many tissues. I-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. Following a rise in intracellular calcium, I-1 is inactivated by calcineurin (or PP2B). Does not inhibit type-2 phosphatases.

References

Endo S.,et al.Biochemistry 35:5220-5228(1996).
Mishra S.,et al.Submitted (NOV-2001) to the EMBL/GenBank/DDBJ databases.
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Connor J.H.,et al.Mol. Cell. Biol. 21:6841-6850(2001).

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$ 395.00
Cat# ALS11930
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