|Application ||WB, IHC-P|
|Dilution||IHC-P (20 µg/ml), WB (1 µg/ml),|
|Other Names||Acetylcholinesterase, AChE, 220.127.116.11, ACHE|
|Target/Specificity||synthetic peptide corresponding to N-terminal residues of human ACHE (N-terminal extended acetylcholinesterase)|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||ACHE / Acetylcholinesterase Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.|
|Cellular Location||Cell junction, synapse Secreted. Cell membrane; Peripheral membrane protein Isoform H: Cell membrane; Lipid-anchor, GPI-anchor; Extracellular side|
|Tissue Location||Isoform H is highly expressed in erythrocytes.|
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Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.
Soreq H.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:9688-9692(1990).
Karpel R.,et al.Exp. Cell Res. 210:268-277(1994).
Yang L.,et al.Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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