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ACHE / Acetylcholinesterase Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - ACHE / Acetylcholinesterase Antibody (N-Terminus) ALS11947
    Anti-Acetylcholinesterase antibody IHC of human skeletal muscle.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P22303
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 68kDa
Dilution IHC-P (20 µg/ml), WB (1 µg/ml),
Additional Information
Gene ID 43
Other Names Acetylcholinesterase, AChE, 3.1.1.7, ACHE
Target/Specificity synthetic peptide corresponding to N-terminal residues of human ACHE (N-terminal extended acetylcholinesterase)
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsACHE / Acetylcholinesterase Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ACHE (HGNC:108)
Function Hydrolyzes rapidly the acetylcholine neurotransmitter released into the synaptic cleft allowing to terminate the signal transduction at the neuromuscular junction. Role in neuronal apoptosis.
Cellular Location Synapse. Secreted. Cell membrane; Peripheral membrane protein [Isoform H]: Cell membrane; Lipid- anchor, GPI-anchor; Extracellular side
Tissue Location Isoform H is highly expressed in erythrocytes.
Research Areas
Citations (0)
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Background

Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.

References

Soreq H.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:9688-9692(1990).
Karpel R.,et al.Exp. Cell Res. 210:268-277(1994).
Yang L.,et al.Submitted (JAN-2001) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

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$ 467.50
Cat# ALS11947
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