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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   CD55 Antibody (clone MEM-118)   

CD55 Antibody (clone MEM-118)

Mouse Monoclonal Antibody

     
  • IHC - CD55 Antibody (clone MEM-118) ALS11972
    Anti-CD55 antibody IHC of human skin, pilosebaceous unit.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, IP, Flo
Primary Accession P08174
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names MEM-118
Calculated MW 41kDa
Dilution IHC-P (10 µg/ml)
Additional Information
Gene ID 1604
Other Names Complement decay-accelerating factor, CD55, CD55, CR, DAF
Target/Specificity HPB-ALL human T cell line
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsCD55 Antibody (clone MEM-118) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD55
Synonyms CR, DAF
Function This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Secreted Isoform 5: Secreted Isoform 7: Cell membrane; Lipid-anchor, GPI-anchor
Tissue Location Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix
Research Areas
Citations (0)

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Background

This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.

References

Caras I.W.,et al.Nature 325:545-549(1987).
Osuka F.,et al.Genomics 88:316-322(2006).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS11972
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