|Application ||WB, IHC-P, ICC, E, RIA, Func|
|Reactivity||Human, Rabbit, Pig|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Serotransferrin, Transferrin, Beta-1 metal-binding globulin, Siderophilin, TF|
|Target/Specificity||Detects human, porcine and rabbit transferrin.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||TF / Transferrin Antibody (clone HTF-14) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
Yang F.,et al.Proc. Natl. Acad. Sci. U.S.A. 81:2752-2756(1984).
Schaeffer E.,et al.Gene 56:109-116(1987).
Hershberger C.L.,et al.Ann. N. Y. Acad. Sci. 646:140-154(1991).
Beutler E.,et al.Blood 96:4071-4074(2000).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
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