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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   SOX2 Antibody (N-Terminus)   

SOX2 Antibody (N-Terminus)

Rabbit Polyclonal Antibody

     
  • IHC - SOX2 Antibody (N-Terminus) ALS12003
    Anti-SOX2 antibody IHC of human brain, cortex.
  • WB - SOX2 Antibody (N-Terminus) ALS12003
    NTERA-2 whole cell extract was resolved by electrophoresis, transferred to nitrocellulose and...
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession P48431
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 34kDa
Dilution IHC-P (1:50)
Additional Information
Gene ID 6657
Other Names Transcription factor SOX-2, SOX2
Target/Specificity Peptide-KLH (N-terminal)
Reconstitution & Storage +4°C or -20°C, Avoid repeated freezing and thawing.
PrecautionsSOX2 Antibody (N-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX2
Function Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Cellular Location Nucleus.
Volume 50 µl
Research Areas
Citations (0)

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Background

Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

References

Stevanovic M.,et al.Mamm. Genome 5:640-642(1994).
Sadler L.A.,et al.Submitted (DEC-1992) to the EMBL/GenBank/DDBJ databases.
Fantes J.,et al.Nat. Genet. 33:461-463(2003).
Takahashi K.,et al.Cell 131:861-872(2007).
Rigbolt K.T.,et al.Sci. Signal. 4:RS3-RS3(2011).

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$ 395.00
Cat# ALS12003
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