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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   B3GAT1 Antibody (clone HCD57)   

B3GAT1 Antibody (clone HCD57)

Mouse Monoclonal Antibody

     
  • IHC - B3GAT1 Antibody (clone HCD57) ALS12019
    Anti-B3GAT1 / CD57 antibody IHC of human adrenal medulla.
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  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, Flo
Primary Accession Q9P2W7
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names HCD57
Calculated MW 38kDa
Dilution Flo (1), IHC-P (10 µg/ml),
Additional Information
Gene ID 27087
Other Names Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1, 2.4.1.135, Beta-1, 3-glucuronyltransferase 1, Glucuronosyltransferase P, GlcAT-P, UDP-GlcUA:glycoprotein beta-1, 3-glucuronyltransferase, GlcUAT-P, B3GAT1, GLCATP
Reconstitution & Storage Store undiluted at 4 degrees C
PrecautionsB3GAT1 Antibody (clone HCD57) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name B3GAT1 (HGNC:921)
Synonyms GLCATP
Function Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group.
Cellular Location Isoform 1: Golgi apparatus membrane {ECO:0000250|UniProtKB:O35789}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:O35789}. Secreted {ECO:0000250|UniProtKB:O35789}
Tissue Location Mainly expressed in the brain.
Volume 50 µl
Research Areas
Citations (0)

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Background

Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo- orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl- sphingomyelin was the most effective, followed by palmitoyl- sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group (By similarity).

References

Mitsumoto Y.,et al.Genomics 65:166-173(2000).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Kakuda S.,et al.J. Biol. Chem. 279:22693-22703(2004).

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$ 395.00
Cat# ALS12019
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