|Application ||WB, IHC-P|
|Dilution||IHC-P (10 µg/ml), WB (1-2 µg/ml),|
|Other Names||A/G-specific adenine DNA glycosylase, 3.2.2.-, MutY homolog, hMYH, MUTYH, MYH|
|Target/Specificity||A synthetic peptide corresponding to amino acids 531-546 of human MYH.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||MUTYH Antibody (aa531-546) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2- OH-A DNA glycosylase activities.|
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Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2- OH-A DNA glycosylase activities.
Slupska M.M.,et al.J. Bacteriol. 178:3885-3892(1996).
Ohtsubo T.,et al.Nucleic Acids Res. 28:1355-1364(2000).
Wang W.,et al.Nucleic Acids Res. 39:44-58(2011).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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