MUTYH Antibody (aa531-546)
Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P |
---|---|
Primary Accession | Q9UIF7 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Calculated MW | 60kDa |
Dilution | IHC-P (10 µg/ml), WB (1-2 µg/ml), |
Gene ID | 4595 |
---|---|
Other Names | A/G-specific adenine DNA glycosylase, 3.2.2.-, MutY homolog, hMYH, MUTYH, MYH |
Target/Specificity | A synthetic peptide corresponding to amino acids 531-546 of human MYH. |
Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
Precautions | MUTYH Antibody (aa531-546) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MUTYH |
---|---|
Synonyms | MYH |
Function | Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities. |
Cellular Location | Nucleus. Mitochondrion {ECO:0000250|UniProtKB:Q99P21} |
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Provided below are standard protocols that you may find useful for product applications.
Background
Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2- OH-A DNA glycosylase activities.
References
Slupska M.M.,et al.J. Bacteriol. 178:3885-3892(1996).
Ohtsubo T.,et al.Nucleic Acids Res. 28:1355-1364(2000).
Wang W.,et al.Nucleic Acids Res. 39:44-58(2011).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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