|Application ||IHC-P, Flo|
|Calculated MW||16331 Da|
|Other Names||Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha, CD235a, GYPA, GPA|
|Reconstitution & Storage||Store undiluted at 4 degrees C|
|Precautions||Glycophorin A+B Antibody (clone HIR2) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein Note=Appears to be colocalized with SLC4A1|
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