|Application ||WB, IHC-P, IF|
|Dilution||IF (1:100-1:400), IHC-P (1:50), WB (2 µg/ml)|
|Other Names||Non-histone chromosomal protein HMG-17, High mobility group nucleosome-binding domain-containing protein 2, HMGN2, HMG17|
|Target/Specificity||Recombinant (partial), C-terminal|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||HMGN2 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).|
|Cellular Location||Nucleus. Cytoplasm. Note=Cytoplasmic enrichment upon phosphorylation|
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Provided below are standard protocols that you may find useful for product applications.
Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation (By similarity).
Landsman D.,et al.J. Biol. Chem. 261:7479-7484(1986).
Landsman D.,et al.Nucleic Acids Res. 17:2301-2314(1989).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Giancotti V.,et al.Eur. J. Biochem. 198:211-216(1991).
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