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ICOSLG / ICOSL / ICOS Ligand Antibody (clone 2D3)

Mouse Monoclonal Antibody

  • IHC - ICOSLG / ICOSL / ICOS Ligand Antibody (clone 2D3) ALS12053
    Anti-ICOSLG / ICOSL antibody IHC of human brain, cortex.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, Flo
Primary Accession O75144
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2D3
Calculated MW 33349 Da
Dilution Flo (0.5 µg/10E6 cells), IHC-P (1:50),
Additional Information
Gene ID 102723996;23308
Other Names ICOS ligand, B7 homolog 2, B7-H2, B7-like protein Gl50, B7-related protein 1, B7RP-1, CD275, ICOSLG, B7H2, B7RP1, ICOSL, KIAA0653
Target/Specificity Human ICOSL/CD275/B7H2
Reconstitution & Storage +4°C. Store undiluted.
PrecautionsICOSLG / ICOSL / ICOS Ligand Antibody (clone 2D3) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms B7H2, B7RP1, ICOSL, KIAA0653
Function Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co- stimulating memory T-cell function (By similarity).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Isoform 1 is widely expressed (brain, heart, kidney, liver, lung, pancreas, placenta, skeletal muscle, bone marrow, colon, ovary, prostate, testis, lymph nodes, leukocytes, spleen, thymus and tonsil), while isoform 2 is detected only in lymph nodes, leukocytes and spleen. Expressed on activated monocytes and dendritic cells.
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$ 395.00
Cat# ALS12053
(40 western blots)
Availability: 5 days
Bulk Size
Seasonal Special on Bulk Order
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