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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IRAK2 / IRAK-2 Antibody   

IRAK2 / IRAK-2 Antibody

Rabbit Polyclonal Antibody

     
  • WB - IRAK2 / IRAK-2 Antibody ALS12090
    Western blot of IRAK-2 in 15 ugs of Jurkat cell lysate using antibody at 1 ug/ml.
  • IHC - IRAK2 / IRAK-2 Antibody ALS12090
    Anti-IRAK2 antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession O43187
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 69kDa
Dilution IHC-P (10 µg/ml), WB (1-3 µg/ml),
Additional Information
Gene ID 3656
Other Names Interleukin-1 receptor-associated kinase-like 2, IRAK-2, IRAK2
Target/Specificity A synthetic peptide of human IRAK-2.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsIRAK2 / IRAK-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IRAK2
Function Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.
Tissue Location Expressed in spleen, thymus, prostate, lung, liver, skeletal muscle, kidney, pancreas and peripheral blood leukocytes.
Research Areas
Citations (0)

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Background

Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

References

Rosati O.,et al.Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Muzio M.,et al.Science 278:1612-1615(1997).
Wesche H.,et al.J. Biol. Chem. 274:19403-19410(1999).
Lin S.-C.,et al.Nature 465:885-890(2010).

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$ 395.00
Cat# ALS12090
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