|Application ||WB, IHC-P|
|Dilution||IHC-P (5 µg/ml), WB (1-2 µg/ml),|
|Other Names||Endophilin-B1, Bax-interacting factor 1, Bif-1, SH3 domain-containing GRB2-like protein B1, SH3GLB1, KIAA0491|
|Target/Specificity||A full-length human Bif-1 recombinant protein was used as immunogen.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||SH3GLB1 / Bif / Endophilin B1 Antibody (clone 30A882.1.1) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion.|
|Cellular Location||Cytoplasm. Golgi apparatus membrane; Peripheral membrane protein. Mitochondrion outer membrane; Peripheral membrane protein. Note=Association with the Golgi apparatus depends on the cell type.|
|Tissue Location||Highly expressed in heart, skeletal muscle, kidney and placenta. Detected at lower levels in brain, colon, thymus, spleen, liver, small intestine, lung and peripheral blood leukocytes.|
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Provided below are standard protocols that you may find useful for product applications.
May be required for normal outer mitochondrial membrane dynamics. Required for coatomer-mediated retrograde transport in certain cells. May recruit other proteins to membranes with high curvature. May promote membrane fusion.
Pierrat B.,et al.Genomics 71:222-234(2001).
Cuddeback S.M.,et al.J. Biol. Chem. 276:20559-20565(2001).
Modregger J.,et al.J. Biol. Chem. 278:4160-4167(2003).
Seki N.,et al.DNA Res. 4:345-349(1997).
Lai C.-H.,et al.Genome Res. 10:703-713(2000).
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