|Application ||WB, IHC-P|
|Dilution||IHC-P (5 µg/ml), WB (0.5-2 µg/ml),|
|Other Names||Tumor necrosis factor receptor superfamily member 19, TRADE, Toxicity and JNK inducer, TNFRSF19, TAJ, TROY|
|Target/Specificity||A mixture of synthetic peptides corresponding to amino acids 29-44, 204-219, and 409-421 of human TROY (Genbank Accession No. AB040434).|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||TNFRSF19 / TROY Antibody (aa29-44) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Highly expressed in prostate. Detected at lower levels in thymus, spleen, testis, uterus, small intestine, colon and peripheral blood leukocytes|
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Can mediate activation of JNK and NF-kappa-B. May promote caspase-independent cell death.
Eby M.T.,et al.J. Biol. Chem. 275:15336-15342(2000).
Kojima T.,et al.J. Biol. Chem. 275:20742-20747(2000).
Chaudhary D.,et al.Submitted (MAR-2000) to the EMBL/GenBank/DDBJ databases.
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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