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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   TRAF5 Antibody (aa77-186, clone 55A219)   

TRAF5 Antibody (aa77-186, clone 55A219)

Mouse Monoclonal Antibody

     
  • WB - TRAF5 Antibody (aa77-186, clone 55A219) ALS12127
    Western blot of TRAF5 using antibody at 2 ug/ml dilution against 10 ug of HeLa cell lysate.
  • IHC - TRAF5 Antibody (aa77-186, clone 55A219) ALS12127
    Anti-TRAF5 antibody IHC of human kidney.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P
Primary Accession O00463
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 55A219 
Calculated MW 64kDa
Dilution IHC-P (10 µg/ml), WB (2 µg/ml),
Additional Information
Gene ID 7188
Other Names TNF receptor-associated factor 5, RING finger protein 84, TRAF5, RNF84
Target/Specificity A fusion protein corresponding to amino acids 77 to 186 of human TRAF5.
Reconstitution & Storage Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.
PrecautionsTRAF5 Antibody (aa77-186, clone 55A219) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRAF5
Synonyms RNF84
Function Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.
Cellular Location Cytoplasm. Cytoplasm, cytosol
Tissue Location Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood
Research Areas
Citations (0)

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Background

Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.

References

Mizushima S.,et al.Gene 207:135-140(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 395.00
Cat# ALS12127
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