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TRAF5 Antibody (aa77-186, clone 55A219)
Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | O00463 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 55A219 |
| Calculated MW | 64kDa |
| Dilution | IHC-P (10 µg/ml), WB (2 µg/ml), |
| Gene ID | 7188 |
|---|---|
| Other Names | TNF receptor-associated factor 5, RING finger protein 84, TRAF5, RNF84 |
| Target/Specificity | A fusion protein corresponding to amino acids 77 to 186 of human TRAF5. |
| Reconstitution & Storage | Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. |
| Precautions | TRAF5 Antibody (aa77-186, clone 55A219) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRAF5 |
|---|---|
| Synonyms | RNF84 |
| Function | Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF- kappa-B by EIF2AK2/PKR. |
| Cellular Location | Cytoplasm. Cytoplasm, cytosol |
| Tissue Location | Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Mediates activation of NF-kappa-B and probably JNK. Seems to be involved in apoptosis. Plays a role in mediating activation of NF-kappa-B by EIF2AK2/PKR.
References
Mizushima S.,et al.Gene 207:135-140(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Ebert L.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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