|Application ||WB, IHC-P|
|Dilution||IHC-P (5 µg/ml), WB (1-3 µg/ml),|
|Other Names||tRNA (cytosine(38)-C(5))-methyltransferase, 220.127.116.11, DNA (cytosine-5)-methyltransferase-like protein 2, Dnmt2, DNA methyltransferase homolog HsaIIP, DNA MTase homolog HsaIIP, M.HsaIIP, PuMet, TRDMT1, DNMT2|
|Target/Specificity||Synthetic peptides corresponding to mouse Dnmt2.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.|
|Precautions||TRDMT1 / DNMT2 Antibody (clone 102B1259.2) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).|
|Tissue Location||Ubiquitous. Higher expression in testis, ovary and thymus and at much lower levels in spleen, prostate, colon, small intestine, and peripheral blood leukocytes|
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Provided below are standard protocols that you may find useful for product applications.
Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).
Yoder J.A.,et al.Hum. Mol. Genet. 7:279-284(1998).
Van den Wyngaert I.,et al.FEBS Lett. 426:283-289(1998).
Okano M.,et al.Nucleic Acids Res. 26:2536-2540(1998).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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